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Dozens of Republican state officials are suing over the White House's COVID-19 vaccine mandate that they say is unconstitutional and threatens business.

President Biden is taking questions from reporters on his top foreign and domestic priorities after talks with world leaders at the G-20 in Rome — and just ahead of the U.N. climate summit.

NPR's David Folkenflik discusses the offseason lockout negotiations with baseball analyst and former player Doug Glanville.

Rameshchandra Patel got COVID-19 early on in the pandemic, when little was known about the virus. His son, Suhash Patel, shares the guiding principles of life his father left as notes in a textbook.

NPR's Steve Inskeep talks to Dr. Anthony Fauci, the nation's top infectious disease expert, about the omicron variant, and how the U.S. should respond to its spread.

Congress faces a Friday deadline to keep federal agencies funded and avoid a partial shutdown, while Democrats push to pass the remainder of President Biden's spending agenda.

With a top Trump-appointed banking regulator stepping down, consumer financial protection groups say the new head of the FDIC should crack down on lenders charging interest rates of 100% or more.

How do artists these days think about their work in our social media world? Sites like Instagram and YouTube are changing the way art is consumed, marketed and made.

On the fourth day of Derek Chauvin's trial for the murder of George Floyd, the courtroom's focus shifted to Floyd's drug use and medical evidence.

This year's best pictures include two friends sunbathing on giant shards of ice in Kazakhstan, workers at a red chili factory in Bangladesh and a white mangrove forest in Vietnam.